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Journal of Dental Research
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CONCISE REVIEW

The Association between Generalized Joint Hypermobility and Temporomandibular Joint Disorders: A Systematic Review

P.U. Dijkstra1,2,3,4,*, T.J.B. Kropmans5 and B. Stegenga1

1 Dept. of Oral and Maxillofacial Surgery,
2 Dept. of Rehabilitation,
3 Pain Center,
4 Northern Center for Health Care Research, and
5 Institute for Medical Education, Dept. for Education Development and Quality Assurance, Faculty of Medical Sciences, University of Groningen;

Correspondence: *corresponding author, University Hospital Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands; p.u.dijkstra{at}rev.azg.nl

To analyze conflicting evidence in the literature for the association between temporomandibular joint disorders (TMD) and generalized joint hypermobility (GJH), we performed a bibliographic search. The methodological quality of the 14 papers found was assessed according to 14 criteria. Papers were included in the analysis if the study population was clinically relevant, if range of motion of 2 or more joints was assessed on the left and right sides, and if cases had a TMD. Four studies fulfilled these selection criteria. Data from 3 studies, 113 cases and 95 controls, were available for analysis. Twenty-six cases and five controls were hypermobile (odds ratio, 5.4). In a sensitivity analysis, the odds ratio changed from significant to non-significant in 2 of 5 scenarios. As a result, it is not clear whether GJH is associated with TMD, and more rigorous studies are needed.

Key Words: temporomandibular joint disorder • generalized joint hypermobility • systematic review

Journal of Dental Research, Vol. 81, No. 3, 158-163 (2002)
DOI: 10.1177/154405910208100303
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