This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Macuch, P.J. Articles by Tanner, A.C.R. Search for Related Content PubMed PubMed Citation Articles by Macuch, P.J. Articles by Tanner, A.C.R. Social Bookmarking                         What's this?

Campylobacter Species in Health, Gingivitis, and Periodontitis

Altran Corporation, Boston, MA

A.C.R. Tanner

The Forsyth Institute, 140 Fenway, Boston, MA 02115, USA

At least seven Campylobacter species have been identified from subgingival sites. Campylobacter rectus has been implicated as a periodontal pathogen; however, association with periodontal infections of other Campylobacter species, especially the newly described Campylobacter showae, is unclear. This study examined which Campylobacter species were associated with periodontal health and disease. Subgingival Campylobacter species from initial and established periodontitis were compared with species from periodontally healthy subjects, including subjects with gingivitis. Campylobacter species were isolated on selective media and identified by whole-cell protein profiles (SDS-PAGE). Except for C. rectus, Campylobacter levels were frequently below the detection limit (2-5% of the microbiota) of non-selective culture methods. C. rectus and C. showae, including Campylobacter X, were found more frequently and in higher levels from diseased than from healthy periodontal sites. C. gracilis was the dominant Campylobacter species found in relatively shallow pockets; however, its presence was unrelated to periodontal health or disease. C. concisus was isolated in higher proportions from relatively shallow and healthy sites, compared with deeper pockets. C. curvus was unrelated to periodontal health or disease. Analysis of the study data confirmed the relationship of C. rectus with diseased subgingival sites and indicated that C. showae may also be associated with periodontal disease.

Key Words: Campylobacter • health • gingivitis • periodontal disease • microbiology.

Journal of Dental Research, Vol. 79, No. 2, 785-792 (2000)
DOI: 10.1177/00220345000790021301


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				B. Chaban, K. M. Musil, C. G. Himsworth, and J. E. Hill Development of cpn60-Based Real-Time Quantitative PCR Assays for the Detection of 14 Campylobacter Species and Application to Screening of Canine Fecal Samples Appl. Envir. Microbiol., May 15, 2009; 75(10): 3055 - 3061. [Abstract] [Full Text] [PDF]

				S. D. Mahlen and J. E. Clarridge III Oral Abscess Caused by Campylobacter rectus: Case Report and Literature Review J. Clin. Microbiol., March 1, 2009; 47(3): 848 - 851. [Abstract] [Full Text] [PDF]

				M. Sugimoto, J.-Y. Wu, S. Abudayyeh, J. Hoffman, H. Brahem, K. Al-Khatib, Y. Yamaoka, and D. Y. Graham Unreliability of Results of PCR Detection of Helicobacter pylori in Clinical or Environmental Samples J. Clin. Microbiol., March 1, 2009; 47(3): 738 - 742. [Abstract] [Full Text] [PDF]

				W. Yamazaki-Matsune, M. Taguchi, K. Seto, R. Kawahara, K. Kawatsu, Y. Kumeda, M. Kitazato, M. Nukina, N. Misawa, and T. Tsukamoto Development of a multiplex PCR assay for identification of Campylobacter coli, Campylobacter fetus, Campylobacter hyointestinalis subsp. hyointestinalis, Campylobacter jejuni, Campylobacter lari and Campylobacter upsaliensis J. Med. Microbiol., November 1, 2007; 56(11): 1467 - 1473. [Abstract] [Full Text] [PDF]

				N. M. Wetsch, K. Somani, G. J. Tyrrell, C. Gebhart, R. J. Bailey, and D. E. Taylor Campylobacter curvus-Associated Hepatic Abscesses: a Case Report. J. Clin. Microbiol., May 1, 2006; 44(5): 1909 - 1911. [Abstract] [Full Text] [PDF]

				R. E. Mandrell, L. A. Harden, A. Bates, W. G. Miller, W. F. Haddon, and C. K. Fagerquist Speciation of Campylobacter coli, C. jejuni, C. helveticus, C. lari, C. sputorum, and C. upsaliensis by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Appl. Envir. Microbiol., October 1, 2005; 71(10): 6292 - 6307. [Abstract] [Full Text] [PDF]

				R. Aabenhus, S. L. W. On, B. L. Siemer, H. Permin, and L. P. Andersen Delineation of Campylobacter concisus Genomospecies by Amplified Fragment Length Polymorphism Analysis and Correlation of Results with Clinical Data J. Clin. Microbiol., October 1, 2005; 43(10): 5091 - 5096. [Abstract] [Full Text] [PDF]

				P. S. Kumar, A. L. Griffen, M. L. Moeschberger, and E. J. Leys Identification of Candidate Periodontal Pathogens and Beneficial Species by Quantitative 16S Clonal Analysis J. Clin. Microbiol., August 1, 2005; 43(8): 3944 - 3955. [Abstract] [Full Text] [PDF]

				X. Y. Han, J. J. Tarrand, and D. C. Rice Oral Campylobacter Species Involved in Extraoral Abscess: a Report of Three Cases J. Clin. Microbiol., May 1, 2005; 43(5): 2513 - 2515. [Abstract] [Full Text] [PDF]

				G. Hutter, U. Schlagenhauf, G. Valenza, M. Horn, S. Burgemeister, H. Claus, and U. Vogel Molecular analysis of bacteria in periodontitis: evaluation of clone libraries, novel phylotypes and putative pathogens Microbiology, January 1, 2003; 149(1): 67 - 75. [Abstract] [Full Text] [PDF]