This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Hansel, C. Articles by Geurtsen, W. Search for Related Content PubMed PubMed Citation Articles by Hansel, C. Articles by Geurtsen, W. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB ETHYLENE METHACRYLATE TRIETHYLENE GLYCOL DIMETHACRYLATE Social Bookmarking                         What's this?

Effects of Various Resin Composite (Co)monomers and Extracts on Two Caries-associated Micro-organisms in vitro

Department of Conservative Dentistry and Periodontology

G. Leyhausen

Department of Conservative Dentistry and Periodontology

U.E.H. Mai

Institute for Medical Microbiology, Medical University Hannover, 30623 Hannover, Germany

W. Geurtsen

Department of Conservative Dentistry and Periodontology

Previous studies have shown that extracts of various filling materials, e.g., resin composites, may influence the growth of cariogenic micro-organisms. The purpose of this study was to examine the effects of important resin composite (co)monomers (Bis-GMA, UDMA, TEGDMA, EGDMA) and extracts of two commercial dental composites with similar composition (composite A, Arabesk^TM; composite S, Superlux^TM) on the growth of the two cariogenic bacterial pathogens Streptococcus sobrinus and Lactobacillus acidophilus. It was found that neither the monomers Bis-GMA and UDMA, nor the comonomer EGDMA, nor the extract of composite A influenced the growth of S. sobrinus in the log phase. The comonomer TEGDMA and the extract of composite S were found to stimulate growth in the log phase, but this stimulation was not statistically significant. However, EGDMA, TEGDMA, and the extract of composite S did stimulate the total growth of S. sobrinus. In the assays with L. acidophilus, Bis-GMA, UDMA, and the extract of composite A inhibited the growth in the log phase, whereas TEGDMA stimulated it. Furthermore, EGDMA, TEGDMA, and the extract of composite S stimulated the biomass production of L. acidophilus. We conclude from our results that a release of EGDMA and TEGDMA from resin composites should be avoided due to their growth-stimulating effects on the caries-associated micro-organisms S. sobrinus and L. acidophilus.

Key Words: dental composites • residual monomers • Streptococcus sobrinus • Lactobacillus acidophilus • microbial effects.

Journal of Dental Research, Vol. 77, No. 1, 60-67 (1998)
DOI: 10.1177/00220345980770010601


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				J.P. Santerre, L. Shajii, and B.W. Leung Relation of Dental Composite Formulations To Their Degradation and the Release of Hydrolyzed Polymeric-Resin-Derived Products Critical Reviews in Oral Biology & Medicine, January 1, 2001; 12(2): 136 - 151. [Abstract] [Full Text] [PDF]

				W. Geurtsen Biocompatibility of Resin-Modified Filling Materials Critical Reviews in Oral Biology & Medicine, January 1, 2000; 11(3): 333 - 355. [Abstract] [Full Text] [PDF]