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Clinical Criteria for the Diagnosis of Salivary Gland Hypofunction

M. Navazesh

C. Christensen

The Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104

V. Brightman

University of Pennsylvania School of Dental Medicine, General Clinical Research Center

There is considerable difficulty in the making of initial clinical decisions as to whether a given patient has salivary gland hypofunction, and hence requires additional salivary gland evaluation. This study identified a set of four clinical measures that, together, successfully predicted the presence or absence of salivary gland hypofunction. The four measures were: dryness of lips, dryness of buccal mucosa, absence of saliva produced by gland palpation, and total DMFT; they were derived from discriminant analysis of data collected from 71 individuals with normal and low salivary flow rates. These measures are proposed as criteria for clinical decision-making, as well as for classification of patients in studies of salivary gland dysfunction syndromes. This study also identified unstimulated whole salivary flow rates of 0.12-0.16 mL/ min as the critical range separating individuals with salivary gland hypofunction from those with normal gland function.

Journal of Dental Research, Vol. 71, No. 7, 1363-1369 (1992)
DOI: 10.1177/00220345920710070301
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