Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Hata, S.
Right arrow Articles by Yamada, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hata, S.
Right arrow Articles by Yamada, T.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*GLUCOSE
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Biochemical Mechanisms of Enhanced Inhibition of Fluoride on the Anaerobic Sugar Metabolism by Streptococcus sanguis

S. Hata

Department of Oral Biochemistry, Tohoku University School of Dentistry, Sendai, 980, Japan

Y. Iwami

Department of Oral Biochemistry, Tohoku University School of Dentistry, Sendai, 980, Japan

K. Kamiyama

Department of Oral Biochemistry, Tohoku University School of Dentistry, Sendai, 980, Japan

T. Yamada

Department of Oral Biochemistry, Tohoku University School of Dentistry, Sendai, 980, Japan

The effect of fluoride on acid production by Streptococcus sanguis ATCC 10556 was compared under anaerobic and aerobic conditions. The rate of acid production under constant-pH and pH-free-fall conditions was determined during glucose metabolism by resting cells. Anaerobic glycolysis was inhibited more strongly by fluoride than was aerobic glycolysis. Intracellular levels of 3-phosphoglyceric, 2-phosphoglyceric, and phosphoenolpyruvic acids were lower under anaerobic conditions than under aerobic conditions. Thus, S. sanguis had a low phosphoenolpyruvate (PEP) potential under anaerobic conditions. This low PEP potential was suggested to account for the more effective fluoride inhibition of enolase and, consequently, the reduced transport of sugar by the PEP-dependent phosphotransferase system of this micro-organism.

Journal of Dental Research, Vol. 69, No. 6, 1244-1247 (1990)
DOI: 10.1177/00220345900690060401
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JDRHome page
Y. Iwami, C.F. Schachtele, and T. Yamada
Effect of Sucrose Monolaurate on Acid Production, Levels of Glycolytic Intermediates, and Enzyme Activities of Streptococcus mutans NCTC 10449
Journal of Dental Research, September 1, 1995; 74(9): 1613 - 1617.
[Abstract] [PDF]

Home page
 JDRHome page
N. Guha-Chowdhury, Y. Iwami, T. Yamada, and E.I.F. Pearce
The Effect of Fluorhydroxyapatite-derived Fluoride on Acid Production by Streptococci
Journal of Dental Research, September 1, 1995; 74(9): 1618 - 1624.
[Abstract] [PDF]