Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Oliveby, A.
Right arrow Articles by Dawes, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Oliveby, A.
Right arrow Articles by Dawes, C.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Studies on Fluoride Concentrations in Human Submandibular/Sublingual Saliva and their Relation to Flow Rate and Plasma Fluoride Levels

A. Oliveby

Department of Cariology, School of Dentistry, Karolinska Institutet, Box 4064, S-141 04 Huddinge, Sweden

F. Lagerlof

Department of Cariology, School of Dentistry, Karolinska Institutet, Box 4064, S-141 04 Huddinge, Sweden

J. Ekstrand

College of Dentistry, Specialized Caries Research Center, University of Iowa, Iowa City, Iowa 52242, USA

C. Dawes

Department of Oral Biology, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada R3E OW2

Submandibular/sublingual saliva and blood were collected from five subjects after ingestion of 1 mg fluoride as NaF. An individual collection device, made from a silicone impression material, was used to collect the saliva in 10-minute samples, before and during 2 hr after the fluoride intake. In two separate experiments on each individual, submandibular/sublingual saliva was collected continuously at different flow rates: without stimulation and with gustatory stimulation. Blood was also collected at intervals throughout the experiments. The concentration of fluoride in the submandibularlsublingual saliva was less than that in the plasma but independent of salivary flow rate. The ratio between the saliva and plasma fluoride concentrations at the peak of the mean plasma fluoride concentrations was 0.55 ± 0.13 and 0.69 ± 0.11 in the experiments on unstimulated and stimulated salivary flow rate, respectively. The total amount of the ingested fluoride dose that was excreted through the submandibular/sublingual glands during 130 min was highly correlated with the salivary flow rate. The fraction of the ingested fluoride dose excreted in 2 hr was 0.04 ± 0.02% in the unstimulated saliva and 0.15 ± 0.09% in the stimulated saliva.

Journal of Dental Research, Vol. 68, No. 2, 146-149 (1989)
DOI: 10.1177/00220345890680020901
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JDRHome page
A. Wolff, A. Begleiter, and D. Moskona
A Novel System of Human Submandibular/Sublingual Saliva Collection
Journal of Dental Research, November 1, 1997; 76(11): 1782 - 1786.
[Abstract] [PDF]