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Journal of Dental Research
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Changes of Secretory Ameloblasts in Mini-pig Fetuses Exposed to Ethanol in vivo

M.E. Matthiessen

Anatomy Department A, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark

P. Rømert

Anatomy Department C, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark

After addition of ethanol to the ordinary fodder of pregnant mini-pigs, ultrastructural changes were found in secretory ameloblasts from tooth germs of their mid-term fetuses. Compared with controls, many mitochondria showed abnormal shape and size, and some exhibited deposition of paracrystalline material in the matrix. An abnormal deposition of stippled material intercellularly was also observed. These changes were interpreted as signs of an abnormal secretory function.

Journal of Dental Research, Vol. 67, No. 11, 1402-1404 (1988)
DOI: 10.1177/00220345880670110801
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