Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Miyasaki, K.T.
Right arrow Articles by Wolinsky, L.E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Miyasaki, K.T.
Right arrow Articles by Wolinsky, L.E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Differential Modulation of Adherence of Oral Streptococci by Human Neutrophil Myeloperoxidase

K.T. Miyasaki

Section of Periodontics, Center for the Health Sciences, University of California, Los Angeles, California 90024, Section of Oral Biology, School of Dentistry, Center for the Health Sciences, University of California, Los Angeles, California 90024

P.M. de Camargo

Section of Periodontics, Center for the Health Sciences, University of California, Los Angeles, California 90024

L.E. Wolinsky

Section of Oral Biology, School of Dentistry, Center for the Health Sciences, University of California, Los Angeles, California 90024

In this study, the modulation of adherence of hydrogen peroxide (H2O2)-producing and non-H2O2-producing strains of oral streptococci by the host leukocyte enzyme myeloperoxidase (MPO) was examined. It was found that exposure to MPO decreased adherence of many strains of oral streptococci to saliva-coated hydroxyapatite beads in the presence of exogenous H2O 2 and chloride. The MPO-H2O2-Cl- system increased the adherence of one strain. In the absence of exogenous H 2O2, the MPO-H2O2-Cl- system decreased the adherence of H2O2producing strains only. Glucose increased streptococcal H2O2 production and also increased the anti-adhesive activity of MPO in the absence of exogenous H2O2. We conclude that: (1) host leukocytes can modulate the adherence of oral streptococci via MPO; (2) endogenous production of H 2O2 by the oral streptococci can provide sufficient substrate H2O2 to drive this system; and (3) MPO will exert differential modulatory effects on the adherence of oral streptococci, based in part upon the level of endogenous H2O2 production and in part upon the particular characteristics of the adhesins of the bacteria.

Journal of Dental Research, Vol. 67, No. 10, 1300-1306 (1988)
DOI: 10.1177/00220345880670101101
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JDRHome page
K.T. Miyasaki
Preferential Adsorption of Human Neutrophil Myeloperoxidase Isoform III by Oral Bacteria
Journal of Dental Research, November 1, 1990; 69(11): 1780 - 1783.
[Abstract] [PDF]