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Improvement of the Caries Resistance of Human Dental Roots by a Two-step Conversion of the Root Mineral into Fluoridated Hydroxylapatite

Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands

E. Groenendijk

Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands

N. Ramlochan Tewarie

Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands

F.C.M. Driessens

Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands

Roots of extracted human molars were treated for both 10 and 30 min with a saturated solution of dicalcium phosphate dihydrate (DCPD) of pH 2.4 and subsequently with a 5.3 mmol.L ^-1 solution of sodium fluoride of pH 7.0. The objective of these combined treatments was to convert the highly-soluble root mineral into the less-soluble fluoridated hydroxylapatite, with DCPD as an intermediate, to improve caries resistance. The mineral content of the surface layer was not affected in a significant way.

Roots treated in this way were subjected to 50 mmol.L^-1 acetate buffer solutions of pH 5.5 and with pI_OHA-values of 112, 116, and 122. The proportional reduction of the rate of demineralization (V_dem) of similarly treated roots subjected to buffer solutions of pI_OHA 112 and 116 appeared to be equal initially. Since fluoridated hydroxylapatite is insoluble under these conditions, these findings are in agreement with expectations. The reduction of V_dem amounted to about 45 and 70% for roots treated for 10 and 30 min, respectively.

When roots were treated for 10 and 30 min and then exposed to buffer solutions with a pI_OHA 122, reductions of V_dem of about 30 and 55%, respectively, were found.

Conversion of the root mineral into fluoridated hydroxylapatite can eliminate, in principle, the existing difference in caries susceptibility of the root and of the dental enamel.

Journal of Dental Research, Vol. 67, No. 10, 1254-1256 (1988)
DOI: 10.1177/00220345880670100101


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