This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Abe, K. Articles by Matsumoto, M. Search for Related Content PubMed PubMed Citation Articles by Abe, K. Articles by Matsumoto, M. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB CALCIUM COMPOUNDS CALCIUM, ELEMENTAL METHOXAMINE HYDROCHLORIDE PILOCARPINE POTASSIUM Social Bookmarking                         What's this?

Developmental Changes in the Volumes, Protein, and Some Electrolyte Concentrations of Male and Female Rat Submandibular Saliva Secreted in Response to Methoxamine and Pilocarpine

Department of Oral Biochemistry, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

S. Hidaka

Department of Oral Biochemistry, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

K. Ishibashi

Department of Oral Biochemistry, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

M. Yanabu

Department of Orthodontics, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

K. Kamogashira

Department of Orthodontics, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

T. Itoh

Department of Orthodontics, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

M. Matsumoto

Department of Orthodontics, Fukuoka Dental College, 700, Ta, Sawara-ku, Fukuoka-shi, 814-01, Japan

Saliva secreted in response to methoxamine and pilocarpine was collected from the cannulated ducts of the submandibular glands of male and female rats at weekly intervals from two to 10 weeks of age. It was analyzed for volume and for concentrations of protein, potassium, calcium, and inorganic phosphate. Following the collection of saliva, the submandibular glands were removed and weighed.

The wet weights of the glands increased substantially up to seven weeks of age and then reached almost plateau values in both sexes. The salivary volumes secreted in response to both agents in both sexes were positively correlated with the gland weights, except that after five to six weeks of age there was no correlation between gland weight and methoxamine-stimulated salivary volume. The concentrations of protein, potassium, and inorganic phosphate were inversely related to the flow rates only at relatively low rates of flow. The concentration of calcium was positively correlated with the protein concentration and was independent of the nature of the stimulus and of sex differences during postnatal development.

Journal of Dental Research, Vol. 66, No. 3, 745-750 (1987)
DOI: 10.1177/00220345870660030801


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				G. S. Bedi The Effect of Adrenergic Agonists and Antagonists on the Expression of Proteins in Rat Submandibular and Parotid Glands Critical Reviews in Oral Biology & Medicine, January 1, 1993; 4(3): 565 - 571. [Abstract] [Full Text] [PDF]

				E. Tanaka, T. Habu, A. Letic-Gavrilovic, and K. Abe Changes in Protein Secretion by Rat Submandibular Glands in Response to Isoproterenol, a-Methylnoradrenaline, and Clonidine during Post-natal Development Journal of Dental Research, January 1, 1990; 69(1): 60 - 66. [Abstract] [PDF]

				A. Inanaga, T. Habu, E. Tanaka, T. Taniguch, T. Nishiura, K. Ishibashi, S. Naruse, and K. Abe Age Changes in Secretory Function of Male and Female Rat Parotid Glands in Response to Methoxamine and Pilocarpine Journal of Dental Research, March 1, 1988; 67(3): 565 - 573. [Abstract] [PDF]