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Journal of Dental Research
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Immunocytochemical Evidence for the Coexistence of Catecholestrogen and Catechol-O-methyltransferase in the Rat Parotid Gland

K. Inoue

Department of Oral Anatomy, School of Dentistry, Okayama University, Okayama 700, Japan

I. Yoshizawa

Hokkaido Institute of Pharmaceutical Science, Otaru 047, Japan

C.R. Creveling

Laboratory of Bio-organic Chemistry, NIDDK, NIH, Bethesda, Maryland 20892

Catechol-O-methyltransferase (COMT) (EC 2.1.1.6) and catecholestrogen were localized in the parotid gland of the rat by immunocytochemical methods. Specific immunoreactive deposits for COMT and catecholestrogen were found in the cytoplasm of duct cells, but only those for COMT in myo-epithelial cells. The pattern of localization of COMT and catecholestrogen in the parotid gland suggests a functional relationship between COMT and catecholestrogen.

Journal of Dental Research, Vol. 66, No. 11, 1627-1629 (1987)
DOI: 10.1177/00220345870660110401
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