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Enhanced Enamel F Uptake by Monocalcium Phosphate Monohydrate Gels

American Dental Association Health Foundation, Paffenbarger Research Center, National Bureau of Standards, Gaithersburg, Maryland 20899

L.C. Chow

American Dental Association Health Foundation, Paffenbarger Research Center, National Bureau of Standards, Gaithersburg, Maryland 20899

E.M. Yamada

American Dental Association Health Foundation, Paffenbarger Research Center, National Bureau of Standards, Gaithersburg, Maryland 20899

W.E. Brown

American Dental Association Health Foundation, Paffenbarger Research Center, National Bureau of Standards, Gaithersburg, Maryland 20899

Application of DCPD-forming solutions has been shown to increase substantially the enamel reactivity toward F. The effectiveness of a variation of this treatment procedure, in which the DCPD-forming solution was replaced by a viscous carboxymethylcellulose gel containing monocalcium phosphate monohydrate (MCPM), was evaluated by use of 12 extracted human molars. The MCPM gel was highly effective in enhancing the F uptake by enamel. The mean F uptakes by teeth treated with MCPM gel, followed by exposure to a F solution, were 3972 ( ± 565), 2383 ( ± 312), and 1751 (± 313) ppm, respectively, in the outer 5-, 10-, and 15-µm depths in enamel. These uptakes were 2374, 1273, and 852 ppm more than those of the control teeth. Because the F solution was undersaturated with respect to CaF2, the F incorporated into the enamel was believed to be in apatitic form and not as CaF2. The MCPM gel has advantages over the DCPD-forming solution because (1) much longer gel-tooth contact times can be achieved, and (2) the treatment agent can readily be delivered to specific sites where the tooth needs the protection most.

Journal of Dental Research, Vol. 66, No. 10, 1523-1526 (1987)
DOI: 10.1177/00220345870660100201


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