This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Hellwig, E. Articles by Wagner, H. Search for Related Content PubMed PubMed Citation Articles by Hellwig, E. Articles by Wagner, H. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB SODIUM FLUORIDE Social Bookmarking                         What's this?

The Influence of Plaque on Reaction Mechanism of MFP and NaF in vivo

Department of Operative Dentistry, School of Dentistry, University of Marburg, Georg-Voigt-Str. 3, D-3550 Marburg, Federal Republic of Germany

J. Klimek

Department of Operative Dentistry, School of Dentistry, University of Marburg, Georg-Voigt-Str. 3, D-3550 Marburg, Federal Republic of Germany

H. Wagner

Department of Operative Dentistry, School of Dentistry, University of Marburg, Georg-Voigt-Str. 3, D-3550 Marburg, Federal Republic of Germany

A modified Intra-oral Cariogenicity Test was used to study the influence of plaque on the reaction mechanism of sodium monofluorophosphate (MFP) or sodium fluoride (NaF) in either sound or demineralized enamel in vivo. Volunteer students, wearing mouth appliances holding enamel blocks, rinsed their mouths with MFP or NaF solution (1000 ppm F-) three times a day. The amount of loosely-bound and acquired fluoride was determined after an experimental period of five days in plaque-covered, demineralized (PCD); clean, demineralized (CD); plaque-covered, sound (PCS); and clean sound enamel (CS). While no measurable loosely-bound fluoride could be found after MFP treatment, NaF caused deposition of a significant amount of alkali-soluble fluoride in all experimental groups. After MFP rinses, fluoride concentration in the enamel was increased in the following order: CS, PCS, CD, and PCD. After NaF treatment, demineralized enamel exhibited a higher fluoride acquisition when compared with sound enamel. Plaque had a minor effect on F- acquisition. It is concluded that demineralization of enamel enhances F- uptake from both NaF and MFP solutions. In the presence of plaque, F- acquisition was additionally increased only after MFP rinses in vivo.

Journal of Dental Research, Vol. 66, No. 1, 46-49 (1987)
DOI: 10.1177/00220345870660011001


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				D.J. White The Application of in Vitro Models to Research on Demineralization and Remineralization of the Teeth Advances in Dental Research, November 1, 1995; 9(3): 175 - 193. [Abstract] [PDF]

				E.I.F. Pearce and G.H. Dibdin The Diffusion and Enzymic Hydrolysis of Monofluorophosphate in Dental Plaque Journal of Dental Research, February 1, 1995; 74(2): 691 - 697. [Abstract] [PDF]

				E. Hellwig Fluoride Retention in Dentin after Topical Application of Aminefluoride Journal of Dental Research, September 1, 1992; 71(9): 1558 - 1560. [Abstract] [PDF]

				J.M. ten Cate and J.D.B. Featherstone Mechanistic Aspects of the Interactions Between Fluoride and Dental Enamel Critical Reviews in Oral Biology & Medicine, January 1, 1991; 2(3): 283 - 296. [Abstract] [Full Text] [PDF]

				K. Trautner and J. Einwag Influence of Milk and Food on Fluoride Bioavailability from NaF and Na2FPO 3 in Man Journal of Dental Research, January 1, 1989; 68(1): 72 - 77. [Abstract] [PDF]