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Journal of Dental Research
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Fluoride Distribution in Enamel after in vitro Caries-like Lesion Formation

B.H. Clarkson

Dows Institute for Dental Research, Division of Cariology, College of Dentistry, The University of Iowa, Iowa City, Iowa 52242

J.S. Wefel

Dows Institute for Dental Research, Division of Cariology, College of Dentistry, The University of Iowa, Iowa City, Iowa 52242

F.F. Feagin

Department of Physiology & Biophysics, University of Alabama at Birmingham, Birmingham, Alabama 35294

Using a microdissection technique to obtain samples from carious and adjacent sound enamel, we compared the fluoride concentrations in surface and subsurface enamel. Undialyzed and dialyzed gels were used to create lesions with and without negatively birefringent surface zones, respectively. The fluoride concentration in the surface enamel of the lesions was always greater than that in the corresponding sound enamel, as was the subsurface fluoride concentrations of caries lesions compared with adjacent sound enamel at the same depth.

Journal of Dental Research, Vol. 65, No. 7, 963-966 (1986)
DOI: 10.1177/00220345860650071301
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F.A. Damato, R. Strang, and K.W. Stephen
Comparison of Solution- and Gel-prepared Enamel Lesions-an in vitro pH-cycling Study
Journal of Dental Research, August 1, 1988; 67(8): 1122 - 1125.
[Abstract] [PDF]