Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Shahed, A.R.
Right arrow Articles by Allmann, D.W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Shahed, A.R.
Right arrow Articles by Allmann, D.W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Effect of NaF on Rat Parotid Gland Amylase Activity and cAMP Concentration in vitro and in vivo

A.R. Shahed

Department of Biochemistry, Indiana University School of Medicine, Indianapolis, Indiana 46223

J. Bondi

Department of Biochemistry, Indiana University School of Medicine, Indianapolis, Indiana 46223

D.W. Allmann

Department of Biochemistry, Indiana University School of Medicine, Indianapolis, Indiana 46223

The effect of NaF on the cAMP concentration in and amylase secretion from rat parotid glands in vitro and in vivo was investigated. In vitro, NaF (0.05 to 10 mmol/1 ) was found to increase significantly amylase secretion and cAMP concentration in parotid gland slices. In vivo, male rats injected intraperitoneally with 15 mg Flkg body weight as NaF had a significantly lower glandular amylase activity and higher plasma amylase activity than did the control rats injected with 0.9% NaCl. The fluoride concentration both in the parotid gland and plasma was highest at 30 min after injection and decreased with time in the fluoride-injected group. The concentration of the parotid gland cAMP in the fluoride-injected group was significantly higher than that in the control group. On the basis of these results, it is suggested that NaF, both in vitro and in vivo, increases the cAMP concentration, which subsequently stimulates amylase secretion from rat parotid glands.

Journal of Dental Research, Vol. 64, No. 9, 1126-1129 (1985)
DOI: 10.1177/00220345850640090501
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JDRHome page
A.R. Shahed and D.W. Allmann
Effect of NaF on cAMP Accumulation, cAMP-dependent Protein Kinase Activity in, and Amylase Secretion from, Rat Parotid Gland Cells
Journal of Dental Research, February 1, 1988; 67(2): 462 - 466.
[Abstract] [PDF]

Home page
 JDRHome page
G.M. Whitford, D.W. Allmann, and A.R. Shahed
Topical Fluorides: Effects on Physiologic and Biochemical Processes
Journal of Dental Research, May 1, 1987; 66(5): 1072 - 1078.
[Abstract] [PDF]