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Journal of Dental Research
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Changes in Dentin Appositional Rates During Pregnancy and Lactation in Rats

S.C. Miller

Department of Pharmacology, Division of Radiobiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112

T.H. Omura

Department of Pharmacology, Division of Radiobiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112

L.J. Smith

Department of Pharmacology, Division of Radiobiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112

Dentin appositional rates were determined in pregnant and lactating rats and compared with those in non-pregnant, age-matched controls. Appositional rates were calculated from measurements of distance between fluorescent mineralized tissue markers. There were significant increases in dentin apposition during pregnancy, with the greatest increases seen in the first two weeks. Dentin appositional rates decreased significantly during mid-lactation. These results indicate that homeostatic changes during pregnancy and lactation affect mineralized tissue accretion.

Journal of Dental Research, Vol. 64, No. 8, 1062-1064 (1985)
DOI: 10.1177/00220345850640080701
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S.C. Miller, J. Hunziker, M. Mecham, and T.J. Wronski
Intermittent Parathyroid Hormone Administration Stimulates Bone Formation in the Mandibles of Aged Ovariectomized Rats
Journal of Dental Research, August 1, 1997; 76(8): 1471 - 1476.
[Abstract] [PDF]