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Journal of Dental Research
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Sugar Clearance from Saliva and Intra-oral Spaces

D. Goulet

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

F. Brudevold

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

A. Tehrani

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

F. Attarzadeh

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces and could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths with solutions of 5, 10, or 25% glucose. Samples were obtained from a pair of spaces and from saliva at standard intervals and were analyzed for glucose. The rate of glucose clearance was consistently slower from the spaces than from bulk saliva, as shown by higher concentrations and longer clearance times for the spaces. The clearance curves were similar in shape and were rectilinear when the logarithms of the concentrations were plotted against time. The rate of clearance from the spaces appears to be characteristic for an individual, as was also true of salivary clearance.

Journal of Dental Research, Vol. 64, No. 3, 411-415 (1985)
DOI: 10.1177/00220345850640030301
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