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Journal of Dental Research
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Plasma Fluoride Levels in Man Following Intake of SnF2 in Solution or Toothpaste

J.E. Ellingsen

Department of Pedodontics and Caries Prophylaxis, Dental Faculty, University of Oslo, Oslo, Norway

J. Ekstrand

Department of Cariology, School of Dentistry, Box 4064, S-141 04 Huddinge, Sweden

The degree and rate of fluoride absorption in five volunteers were studied after ingestion of SnF 2 and NaF solutions or SnF2 toothpaste. The fluoride concentration in plasma was followed for eight hours. The relative bio-availability of fluoride was calculated and was similar for both the NaF and SnF2 solutions, although the latter solution showed a somewhat faster absorption rate. The bio-availability of fluoride from the SnF2 dentifrice was 85%.

Journal of Dental Research, Vol. 64, No. 10, 1250-1252 (1985)
DOI: 10.1177/00220345850640101401
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J. Ekstrand
Pharmacokinetic Aspects of Topical Fluorides
Journal of Dental Research, May 1, 1987; 66(5): 1061 - 1065.
[Abstract] [PDF]