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Journal of Dental Research
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Collagen and Prostaglandin Synthesis in Force-stressed Periodontal Ligament in vitro

G.W. Duncan

Department of Preventive Dental Science

E.H.K. Yen

Department of Preventive Dental Science

E.T. Pritchard

Department of Oral Biology, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0W3

D.M. Suga

Department of Preventive Dental Science

.4 periodontal organ culture system capable of receiving orthodontic type forces was developed. Histalogical, radioautographical, collagen, and prostaglandin synthetic data demonstrated the vitality of the organ over a 24-hour period of culture. Significant increases in the proportion of type III collagen synthesized during periods of active stress were found, but no alterations in relative levels of prostaglandins synthesized during periods of force application were discernible.

Journal of Dental Research, Vol. 63, No. 5, 665-669 (1984)
DOI: 10.1177/00220345840630051201
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