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Journal of Dental Research
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Effect of Eugenol on Constrictor Responses in Blood Vessels of the Rabbit Ear

W.R. Hume

UCLA School of Dentistry, The Center for the Health Sciences, LosAngeles, California 90024

Aqueous solutions of eugenol depressed vasoconstrictor responses to exogenous norepinephrine (NE), histamine, and peri-arterial sympathetic nerve stimulation in the isolated central artery of the rabbit ear and in the isolated perfused whole rabbit ear. The depression was dose- and time-dependent, and was slowly reversible. Eugenol appeared to act as an inhibitor of smooth muscle contractility.

Journal of Dental Research, Vol. 62, No. 9, 1013-1015 (1983)
DOI: 10.1177/00220345830620090301


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