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Journal of Dental Research
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Biologic Evaluation of a Silver-Copper-Germanium Dental Casting Alloy and a Gold-Germanium Coating Alloy

J.D. Townsend

Department of Restorative Dentistry

A.I. Hamilton

Department of Restorative Dentistry

L. Sbordone

Department of Periodontics, University of Washington, School of Dentistry, Seattle, Washington 98195

An Ag-Cu-Ge alloy and an Au-Ge alloy were evaluated for their hemolytic effect on rabbit blood, cytotoxicity to {alpha}-L fibrosarcoma cells, and allergenic effect on guinea pigs. Neither alloy evoked a significant hemolytic response; cytotoxicity, and that of pure germanium, was no greater than that of ZOE cement; and, on the basis of the guinea pig response, the potential human allergenic response was considered to be Grade I (weak) and Grade II (mild), respectively.

Journal of Dental Research, Vol. 62, No. 8, 899-903 (1983)
DOI: 10.1177/00220345830620081001
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H.F. Morris, M. Manz, W. Stoffer, and D. Weir
Casting Alloys: the Materials and "the Clinical Effects"
Advances in Dental Research, September 1, 1992; 6(1): 28 - 31.
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