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Journal of Dental Research
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The Presence of Fucosyltransferases with Different Substrate Specificity in Human Parotid Saliva

H. Tamagawa

Department of Preventive Dentistry, Osaka University Dental School, 3-48, Nakanoshima 4-chome, Kita-ku, Osaka 530, Japan

E. Inoshita

Department of Preventive Dentistry, Osaka University Dental School, 3-48, Nakanoshima 4-chome, Kita-ku, Osaka 530, Japan

S. Shibata

Department of Preventive Dentistry, Osaka University Dental School, 3-48, Nakanoshima 4-chome, Kita-ku, Osaka 530, Japan

S. Shizukuishi

Department of Preventive Dentistry, Osaka University Dental School, 3-48, Nakanoshima 4-chome, Kita-ku, Osaka 530, Japan

A. Tsunemitsu

Department of Preventive Dentistry, Osaka University Dental School, 3-48, Nakanoshima 4-chome, Kita-ku, Osaka 530, Japan

Using glycoproteins and milk oligosaccharides as substrate acceptors, we demonstrated at leaet two fucosyltransferases in human parotid saliva. One enzyme transferred L-fucose from GDP-fucose to the C-3 position of N-acetylglucosamine or glucose residue of oligosaccharide chains, and the other transferred to the C-4 position of N-acetylglucosamine residue of oligosaccharide chains.

Journal of Dental Research, Vol. 62, No. 7, 811-814 (1983)
DOI: 10.1177/00220345830620070701
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H. Tamagawa, K. Iwakura, A. Amano, S. Shizukuishi, and A. Tsunemitsu
Substrate Specificity of Fucosyltransferase Purified from Human Parotid Saliva
Journal of Dental Research, March 1, 1987; 66(3): 756 - 760.
[Abstract] [PDF]