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Journal of Dental Research
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Collagenase Activity in Human Saliva

K. Jima

Department of Biochemistry

K. Ando

Department of Periodontology, School of Dentistry, Aichi-Gakuin University, Nagoya 464, Japan

M. Kishi

Department of Periodontology, School of Dentistry, Aichi-Gakuin University, Nagoya 464, Japan

T. Nakashizuka

Department of Periodontology, School of Dentistry, Aichi-Gakuin University, Nagoya 464, Japan

T. Hayakawa

Department of Biochemistry

Fairly high collagenase activity was initially demonstrated in human whole saliva, and the activity from patients with periodontal diseases was statistically higher than that from healthy subjects. Based on some characteristic properties, the collagenase in whole saliva appeared to be of tissue, rather than bacterial, origin.

Journal of Dental Research, Vol. 62, No. 6, 709-712 (1983)
DOI: 10.1177/00220345830620060301
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R.J. Gibbons
Bacterial Adhesion to Oral Tissues: A Model for Infectious Diseases
Journal of Dental Research, May 1, 1989; 68(5): 750 - 760.
[Abstract] [PDF]