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Journal of Dental Research
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Changes in Protein Composition of Saliva from Radiation-induced Xerostomia Patients and Its Effect on Growth of Oral Streptococci

R.A. Cowman

Dental Research Unit, Miami Veterans Administration Medical Center, Miami, Florida 33125

S.S. Baron

Dental Research Unit, Miami Veterans Administration Medical Center, Miami, Florida 33125

A.H. Glassman

Dental Service, Miami Veterans Administration Medical Center, Miami, Florida 33125

M.E. Davis

Dental Service, Miami Veterans Administration Medical Center, Miami, Florida 33125

A.M. Strosberg

Dental Service, Miami Veterans Administration Medical Center, Miami, Florida 33125

Clarified and dialyzed mixed saliva-water rinses, obtained from patients receiving radiation treatment of the major salivary glands, exhibited quantitative reductions in total protein content and qualitative changes in protein composition. Radiation or post-radiation saliva preparations supported enhanced growth of Streptococcus mutans, but reduced growth of Streptococcus sanguis relative to growth on pretreatment saliva.

Journal of Dental Research, Vol. 62, No. 3, 336-340 (1983)
DOI: 10.1177/00220345830620030601
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