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Journal of Dental Research
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Synergistic Inhibitory Effect of Zinc and Hexetidine on in vitro Growth and Acid Production of Streptococcus mutans

J.E. Moermann

Dental Institute, University of Zurich, Department of Cariology, Periodontology, and Preventive Dentistry, Zurich 8028, Switzerland

H.R. Muehlemann

Dental Institute, University of Zurich, Department of Cariology, Periodontology, and Preventive Dentistry, Zurich 8028, Switzerland

The combined effect of Zn and hexetidine on Streptococcus mutans OMZ 176 growth and acid production was investigated in vitro. Since the minimum inhibitory and bactericidal concentration of zinc and hexetidine in combination was significantly, lower than when applied separately, a synergistic antimicrobial action was evident.

Journal of Dental Research, Vol. 62, No. 2, 135-137 (1983)
DOI: 10.1177/00220345830620021001
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