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Journal of Dental Research
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Effects of Composite Restorations on the Periodontal Membrane in Monkeys

C.E. Nasjleti

Veterans Administration Medical Center and The University of Michigan, Ann Arbor, Michigan 48105

W.A. Castelli

Veterans Administration Medical Center and The University of Michigan, Ann Arbor, Michigan 48105

R.G. Caffesse

Veterans Administration Medical Center and The University of Michigan, Ann Arbor, Michigan 48105

We evaluated the histopathological response of the periodontal membrane to intentionolly-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammation that subsided with the subsequent formation of a fibrous capsule. However, the periodontal membrane adjacent to the composite resin restorations demonstrated chronic inflammation. It was concluded that the composite evoked chronic inflammatory responses of the periodontal tissues in monkeys.

Journal of Dental Research, Vol. 62, No. 1, 75-78 (1983)
DOI: 10.1177/00220345830620011801
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C.T. Hanks, S.E. Strawn, J.C. Watahai, and R.G. Craig
Cytotoxic Effects of Resin Components on Cultured Mammalian Fibroblasts
Journal of Dental Research, November 1, 1991; 70(11): 1450 - 1455.
[Abstract] [PDF]