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Journal of Dental Research
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Association of Lipids with Proteins and Glycoproteins in Human Saliva

B.L. Slomiany

Gastroenterology Research Laboratory, Department of Medicine, New York Medical College, Research Center, Metropolitan Hospital, New York, New York 10029

H. Witas

Gastroenterology Research Laboratory, Department of Medicine, New York Medical College, Research Center, Metropolitan Hospital, New York, New York 10029

V.L.N. Murty

Gastroenterology Research Laboratory, Department of Medicine, New York Medical College, Research Center, Metropolitan Hospital, New York, New York 10029

A. Slomiany

Gastroenterology Research Laboratory, Department of Medicine, New York Medical College, Research Center, Metropolitan Hospital, New York, New York 10029

I.D. Mandel

Division of Preventive Dentistry, School of Dental and Oral Surgery, Columbia University, New York, New York 10032

The distribution of lipids in the fractions of parotid and submandibular saliva following Bio-Gel A-50 column chromatography was measured. Over 50% of the total lipids of submandibular saliva was found in the fraction which contained mainly the high-molecular-weight glycoprotein. This fraction also contained most of the glycolipids, free fatty acids, phospholipids, and cholesterol. In the parotid saliva, the fraction containing the basic glycoprotein (the major glycoprotein fraction of parotid saliva) contained 35% of the total saliva lipids and was enriched in phospholipids ana cholesterol esters.

Journal of Dental Research, Vol. 62, No. 1, 24-27 (1983)
DOI: 10.1177/00220345830620010601
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