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Journal of Dental Research
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Bacterial Invasion of Pulpal Dentin Wall in vitro

E.S. Akpata

Department of Restorative Dentistry, College of Medicine, University of Lagos, P.M.B. 12003, Lagos, Nigeria

H. Blechman

Department of Endodontics, New York University College of Dentistry, 421 First Avenue, New York, New York 10010

Instrumented root canals of extracted human teeth were inoculated with known pulpal bacterial isolates. The inoculated teeth were immersed in the appropriate culture media and incubated at 37° C for varying periods. Streptococci multiplied in the root canals and invaded the radicular dentinal tubules. The extent of bacterial invasion was time-dependent. This experimental model may be useful in investigating the effect of intra-canal medicaments on microorganisms lodged in the pulpal dentin wall.

Journal of Dental Research, Vol. 61, No. 2, 435-438 (1982)
DOI: 10.1177/00220345820610021401
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