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Journal of Dental Research
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Salivary Protein Polymorphisms in Caries-free and Caries-active Adults

L.C. Anderson

Department of Oral Biology, University of Washington, H.S. Bldg. 147 SB-22, Seattle, Washington 98195

B.L. Lamberts

Biochemistry Division, Naval Dental Research Institute, Great Lakes, Illinois 60088

W.F. Bruton

Biochemistry Division, Naval Dental Research Institute, Great Lakes, Illinois 60088

Several salivary proteins are known to exhibit genetic polymorphism, and this study was undertaken to determine whether there was an association of caries experience with specific parotid salivary protein phenotypes. Parotid saliva collected from 46 caries-free and 47 caries-active naval recruits was subjected to SDS, anionic, and cationic polyacrylamide slab gel electrophoresis. Distributions of the acidic proline-rich (Pr), parotid acidic (Pa), double band (Db), parotid size variant (Ps), parotid middle band (Pm), and parotid basic (Pb) protein phenotypes were similar in both caries-free and caries-active subjects. Further, overall protein patterns on SDS, anionic, and cationic slab gels did not differ between the two groups.

Journal of Dental Research, Vol. 61, No. 2, 393-396 (1982)
DOI: 10.1177/00220345820610020501
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