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Journal of Dental Research
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Increased Collagen Synthesis by Gingival Fibroblasts Derived from a Papillon-Lefevre Patient

H.S. Cheung

Rheumatology Section, Department of Medicine, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226

R.K. Landow

Department of Medicine (Dermatology), Los Angeles County, University of Southern California School of Medicine, Los Angeles, California 90033

M. Bauer

Department of Medicine (Dermatology), Los Angeles County, University of Southern California School of Medicine, Los Angeles, California 90033

Both skin and gingival fibroblasts in the Papillon-Lefévre patient synthesized Type I and Type III collagen in a ratio very similar to fibroblasts of control cells. The only abnormality appeared to be elevated levels of collagen and protein synthesis by gingival cells derived from the Papillon-Lefévre patient.

Journal of Dental Research, Vol. 61, No. 2, 378-381 (1982)
DOI: 10.1177/00220345820610020101
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