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Journal of Dental Research
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Chronic Candidiasis of the Rat Tongue: A Possible Model for Human Median Rhomboid Glossitis

C.M. Allen

The Ohio State University, College of Dentistry, 305 W. 12th Avenue, Columbus, Ohio 43210

G.G. Blozis

The Ohio State University, College of Dentistry, 305 W. 12th Avenue, Columbus, Ohio 43210

S. Rosen

The Ohio State University, College of Dentistry, 305 W. 12th Avenue, Columbus, Ohio 43210

J.S. Bright

The Ohio State University, College of Dentistry, 305 W. 12th Avenue, Columbus, Ohio 43210

Ten female Sprague-Dawley rats were inoculated orally with a suspension of viable Candida albicans. Lesions were induced on the posterior midline dorsum of the tongue in seven of ten animals. The clinical and histologic appearance of these lesions was similar to human median rhomboid glossitis.

Journal of Dental Research, Vol. 61, No. 11, 1287-1291 (1982)
DOI: 10.1177/00220345820610111501
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