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Journal of Dental Research
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Evaluation of Salivary IgA Antibodies to Cariogenic Microorganisms in Children. Correlation with Dental Caries Activity

R.W. Bolton

Departments of Oral Biology and Dental Hygiene, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583

G.L. Hlava

Departments of Oral Biology and Dental Hygiene, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583

Children were examined for caries activity, and their salivary IgA was evaluated for reactivity to antigens of cariogenic bacteria by an enzyme-linked immunosorbent assay (ELISA). IgA levels to Streptococcus mutans were higher in children with no detectable caries. Analysis of IgA specific for Lactobacillus casei, teichoic acid, and glucan revealed no protective role for these specificities in children.

Journal of Dental Research, Vol. 61, No. 11, 1225-1228 (1982)
DOI: 10.1177/00220345820610110201
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