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Journal of Dental Research
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Effects of Parasympathomimetic and Sympathomimetic Drugs on the Secretion and Composition of Rat Sublingual Saliva

K. Abe

Department of Oral Biochemistry, Gifu College of Dentistry, Gifu, Japan

Y. Yokota

Department of Oral Biochemistry, Gifu College of Dentistry, Gifu, Japan

C. Dawes

Department of Oral Biology, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada R3E 0W3

The sublingual glands of adult, male rats secreted considerable volumes of saliva in response to several cholinergic agonists, but very little in response to {alpha}-adrenergic stimuli and none in response to a β-adrenergic agonist. The types of proteins secreted were quite different from those in submandibular and parotid saliva or serum, and were largely independent of the nature of the stimulus. However, some differences in staining intensity of electrophoretic patterns occurred both between stimuli and with the same stimulus used on different rats.

Journal of Dental Research, Vol. 61, No. 1, 52-56 (1982)
DOI: 10.1177/00220345820610011201


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