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Journal of Dental Research
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Susceptibility of Rats, Hamsters, and Mice to Carious Infection by Streptococcus mutans Serotype c and d Organisms

Takashi Ooshima

Departments of Pedodontics and Oral Microbiology, Osaka University Dental School, Nakanoshima, Kita-ku, Osaka 530, Japan

Shizuo Sobue

Departments of Pedodontics and Oral Microbiology, Osaka University Dental School, Nakanoshima, Kita-ku, Osaka 530, Japan

Shigeyuki Hamada

Departments of Pedodontics and Oral Microbiology, Osaka University Dental School, Nakanoshima, Kita-ku, Osaka 530, Japan

Shozo Kotani

Departments of Pedodontics and Oral Microbiology, Osaka University Dental School, Nakanoshima, Kita-ku, Osaka 530, Japan

Susceptibility of rats, hamsters, and mice to carious infection by S. mutans serotypes c and d was compared. S. mutans serotype c induced a similar level of carious lesions at experimental periods of 68, 82, and 98 d in rats, hamsters, and mice, respectively. On the other hand, S. mutans serotype d developed a high level of caries at those experimental periods in rats and hamsters, whereas in mice it showed weak caries activity.

Journal of Dental Research, Vol. 60, No. 4, 855-859 (1981)
DOI: 10.1177/00220345810600041701
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