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Journal of Dental Research
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Utilization of Hydroxyapatite Adsorbable Salivary Proteins as Growth Substrates for Plaque-forming Oral Streptococci

R.A. Cowman

Dental Research Unit, Miami VA Medical Center, Miami, Florida 33125, Laboratory of Oral Microbiology, Department of Microbiology, University of Miami, Miami, Florida 33125

S.J. Baron

Dental Research Unit, Miami VA Medical Center, Miami, Florida 33125, Laboratory of Oral Microbiology, Department of Microbiology, University of Miami, Miami, Florida 33125

R.J. Fitzgerald

Dental Research Unit, Miami VA Medical Center, Miami, Florida 33125, Laboratory of Oral Microbiology, Department of Microbiology, University of Miami, Miami, Florida 33125

Hydroxyapatite-treated clarified mixed saliva showed a marked reduction in growth-supportive activity for Streptococcus mutans. Isoelectrophoretic analysis revealed that proteins specifically attacked by S. mutans were among those adsorbed by HA. The proteins desorbed from HA-supported growth of S. mutans at levels comparable to untreated saliva.

Journal of Dental Research, Vol. 60, No. 10, 1803-1808 (1981)
DOI: 10.1177/00220345810600101201
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R.A. Cowman, S.S. Baron, R.J. Fitzgerald, R.E. Stuchell, and I.D. Mandel
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