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Journal of Dental Research
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Isolated Parotid Acinar Cells from DL-Isoproterenol-treated Rats. A Cellular Model for Cystic Fibrosis

J.A. Mangos

Departments of Basic Dental Sciences and Pediatrics, Colleges of Medicine and Dentistry, J. H. Miller Health Center, Gainesville, Florida 32610

R.L. Boyd

Departments of Basic Dental Sciences and Pediatrics, Colleges of Medicine and Dentistry, J. H. Miller Health Center, Gainesville, Florida 32610

D. Bouchlas

Departments of Basic Dental Sciences and Pediatrics, Colleges of Medicine and Dentistry, J. H. Miller Health Center, Gainesville, Florida 32610

W. Farnham

Departments of Basic Dental Sciences and Pediatrics, Colleges of Medicine and Dentistry, J. H. Miller Health Center, Gainesville, Florida 32610

The morphology and composition of isolated acinar cells from the enlarged parotid glands of rats treated chronically with DL-isoproterenol were investigated and compared with isolated acinar cells from parotids of control untreated rats. Changes similar to those observed in parotid acinar cells from patients with cystic fibrosis were demonstrated.

Journal of Dental Research, Vol. 60, No. 1, 80-85 (1981)
DOI: 10.1177/00220345810600011601
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