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Journal of Dental Research
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Effect of Autonomic Agents on the Secretion of N-Acetyl-β-Glucosaminidase of Mouse Submaxillary Gland

Masahiko Hiramatsu

Department of Dental Pharmacology

Keiko Hatakeyama

Department of Dental Pharmacology

Kazuo Hosoi

Oral Physiology, Josai Dental University, Keyakidai, Sakado, Saitama 350-02, Japan

Naomi Minami

Department of Dental Pharmacology

The secretion of N-acetyl-β-glucosaminidase of mouse submaxillary gland into saliva was stimulated by norepinephrine and phenylephrine but not by pilocarpine and isoproterenol. The stimulative effects of the {alpha}-adrenergic agents were inhibited by {alpha}-blockers, phentolamine, and phenoxybenzamine. These results suggest that the secretion of the enzyme is regulated through {alpha}-adrenergic receptors.

Journal of Dental Research, Vol. 59, No. 8, 1439-1441 (1980)
DOI: 10.1177/00220345800590081301
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[Abstract] [PDF]