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Bacterial Penetration of Human Dentin in vitro

Departments of Oral Biology, Cell and Molecular Biology, and Physiology, Medical College of Georgia, Schools of Dentistry and Medicine, Augusta, Georgia 30912

G.S. Schuster

Departments of Oral Biology, Cell and Molecular Biology, and Physiology, Medical College of Georgia, Schools of Dentistry and Medicine, Augusta, Georgia 30912

D.H. Pashley

Departments of Oral Biology, Cell and Molecular Biology, and Physiology, Medical College of Georgia, Schools of Dentistry and Medicine, Augusta, Georgia 30912

The ability of bacteria to penetrate acid-etched and unetched human dentin was examined in vitro using a split chamber. Results indicate that bacteria can grow through or be filtered by pressure through acid-etched dentin. Unetched dentin, while permitting fluid filtration, restricts bacterial penetration. Penetration of dentin tubules by bacteria reduces the rate of fluid filtration across dentin.

Journal of Dental Research, Vol. 59, No. 8, 1398-1403 (1980)
DOI: 10.1177/00220345800590080701


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