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In vivo and in vitro Study of 90Sr in Developing Rat Molar EnamelThe Dental Research Center and the Department of Pedodontics, University of North Carolina, School of Dentistry, Chapel Hill, North Carolina 27514
The Dental Research Center and the Department of Pedodontics, University of North Carolina, School of Dentistry, Chapel Hill, North Carolina 27514
The Dental Research Center and the Department of Pedodontics, University of North Carolina, School of Dentistry, Chapel Hill, North Carolina 27514 The uptake patterns of 90Sr in developing rat molar enamel were studied in vivo and in vitro. Autoradiographic methods were used that preclude loss or translocation of tracers associated with water-soluble compounds in the sections. In eight-day-old rats injected with the tracer, 90Sr uptake in the enamel was significantly less than for dentin and bone, particularly at early sacrifice times. The uptake pattern of 90Sr was somewhat different from that previously observed for 45Ca. The in vitro experiments indicated that the viable intact enamel organ limits uptake of 90Sr by enamel in both the secretory and maturation phases of enamel formation.
Journal of Dental Research, Vol. 59, No. 12,
2091-2099 (1980) |
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