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Journal of Dental Research
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Evaluation of Irradiated Mandibles Using Emission Tomography, Bone Scans, and Radiography

Michael D. Rohrer

The University of Michigan Medical Center, Ann Arbor, Michigan 48109

Louis T. Kircos

The University of Michigan Medical Center, Ann Arbor, Michigan 48109

James H. Thrall

The University of Michigan Medical Center, Ann Arbor, Michigan 48109

Young Kim

The University of Michigan Medical Center, Ann Arbor, Michigan 48109

Juan V. Fayos

The University of Michigan Medical Center, Ann Arbor, Michigan 48109

This study compared radiographs, bone scans, and computed emission tomograms with histologic findings in irradiated mandibles of adult Rhesus monkeys. Although osteocytes were lost in the path of the beam, many vessels were partially or totally occluded, the periosteum degenerated, the marrow became fibrotic, and cancellous bone proliferated abundantly, no changes were noted with radiography, conventional bone scanning, or computed emission tomograms. These clinical methods of examination may misrepresent the true condition of irradiated bone because of inadequate sensitivity or balance among factors that control radioactive tracer uptake in bone.

Journal of Dental Research, Vol. 59, No. 12, 2032-2037 (1980)
DOI: 10.1177/00220345800590120201
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