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Journal of Dental Research
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IgG Subclasses in Human Periodontal Disease: III. Serum Concentrations of IgG Subclass Immunoglobulins and Circulating Immune Complexes

Bruce F. Mackler

The Dental Science Institute, University of Texas Health Science Center, Houston, Texas 77025

Peter Schur

Department of Medicine, Robert B. Brigham Hospital, Harvard Medical School, Boston, Massachusetts 02111

Thomas Waldrop

Wilford Hall USAF Medical Center, Lackland Air Force Base, Texas

Elbert Coker

The Dental Science Institute, University of Texas Health Science Center, Houston, Texas 77025

Roger Rossen

Department of Microbiology and Immunology, Baylor College of Medicine; and the Laboratory for Immunology Research at the Veterans Administration Hospital, Houston, Texas

No quantitative changes in serum IgG subclass concentrations could be correlated clinically with periodontal disease, despite evidence of restrictive IgG subclass antibody responses in inflamed gingiva. Serum from periodontal patients also lacked circulating immune complexes.

Journal of Dental Research, Vol. 58, No. 7, 1701-1704 (1979)
DOI: 10.1177/00220345790580070901
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