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Journal of Dental Research
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Cellular Regulation of the Metabolism of Androgens in Rat Oral Mucosa. II. Product Activation of 17 β-hydroxysteroid Oxidoreductase Enzyme System

Jozef Vittek

Department of Medicine, New York Medical College, New York 10029, U.S.A., Department of Dentistry, New York Medical College, New York 10029, U.S.A.

Gary G. Gordon

Department of Medicine, New York Medical College, New York 10029, U.S.A., Department of Dentistry, New York Medical College, New York 10029, U.S.A.

Sydney C. Rappaport

Department of Medicine, New York Medical College, New York 10029, U.S.A., Department of Dentistry, New York Medical College, New York 10029, U.S.A.

A. Louis Southren

Department of Medicine, New York Medical College, New York 10029, U.S.A., Department of Dentistry, New York Medical College, New York 10029, U.S.A.

Product activation of 17β-hydroxysteroid oxidoreductase for testosterone and androstenedione was established using the enzyme preparation from rat oral mucosa. It is suggested that this activation could be due to the conformational changes of the enzyme.

Journal of Dental Research, Vol. 58, No. 2, 638-641 (1979)
DOI: 10.1177/00220345790580021801
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