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Journal of Dental Research
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Comparison of the Plaque Microflora in Immunodeficient and Immunocompetent Dental Patients

Lee R. Brown

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Bruce F. Mackler

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Barnet M. Levy

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Thomas E. Wright

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Sandra F. Handler

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Joanne S. Moylan

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Deborah H. Perkins

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

Harris J. Keene

The University of Texas Dental Branch, Dental Science Institute, Houston, Texas 77025

The nature and extent of the immune dysfunctions in 20 immunodeficient patients, as well as the immunocompetence of 22 control subjects, were verified by cell-mediated responsiveness and immunoglobulin quantitations. Comparisons of the microbial composition of supragingival plaque between the two populations showed that a greater number of immunodefcient than control subjects harbored Candida sp. and Staphylococcus sp. Conversely, a lower number of immunodeficient than control subjects harbored Streptococcus mutans. Also, patients with immune dysfunctions had a lower dental caries experience than their immunocompetent counterparts.

Journal of Dental Research, Vol. 58, No. 12, 2344-2352 (1979)
DOI: 10.1177/00220345790580120301


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Microbiol. Mol. Biol. Rev.Home page
H. Marcotte and M. C. Lavoie
Oral Microbial Ecology and the Role of Salivary Immunoglobulin A
Microbiol. Mol. Biol. Rev., March 1, 1998; 62(1): 71 - 109.
[Abstract] [Full Text] [PDF]