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Differential Utilization of Proteins in Saliva from Caries-active and Caries-free Subjects as Growth Substrates by Plaque-forming Streptococci

Dental Research Unit, Miami VA Medical Center; and Department of Microbiology, University of Miami School of Medicine, Miami, Florida 33125

S.J. Schaefer

Dental Research Unit, Miami VA Medical Center; and Department of Microbiology, University of Miami School of Medicine, Miami, Florida 33125

R.J. Fitzgerald

Dental Research Unit, Miami VA Medical Center; and Department of Microbiology, University of Miami School of Medicine, Miami, Florida 33125

D. Rosner

Dental Research Unit, Miami VA Medical Center; and Department of Microbiology, University of Miami School of Medicine, Miami, Florida 33125

I.L. Shklair

Great Lakes Naval Dental Research Institute, Great Lakes Training Center, Great Lakes, Illinois

R.G. Walter

Great Lakes Naval Dental Research Institute, Great Lakes Training Center, Great Lakes, Illinois

Mixed or parotid saliva from caries-active individuals consistently supported better growth of Streptococcus mutans (type c) than that from caries-free individuals. Electrophoretic studies revealed that certain proteins in caries-active salivas were susceptible to microbial attack, but similar proteins in caries-free salivas were refractory.

Journal of Dental Research, Vol. 58, No. 10, 2019-2027 (1979)
DOI: 10.1177/00220345790580101501


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