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Journal of Dental Research
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The Effect of Procion Blue on Certain Metabolic Activities of Streptococcus mutans

E.E. Vicher

Departments of Microbiology and Oral Pathology, University of Illinois at the Medical Center, Chicago, Illinois 60680, USA

M. Iqbal

Departments of Microbiology and Oral Pathology, University of Illinois at the Medical Center, Chicago, Illinois 60680, USA

J.P. Waterhouse

Departments of Microbiology and Oral Pathology, University of Illinois at the Medical Center, Chicago, Illinois 60680, USA

Metabolic activities of S mutans were selectively affected by Procion Blue, known to cause covalent bonds and stable cross links in relation to carbohydrate and protein. In this study, despite the reduction in extra polysaccharide, the level of activity of glucosyltransferase was not significantly changed from the control level and colonial morphology was not transformed from smooth to rough. The results of the investigation imply at least interference with formation of extracellular polysaccharide, possibly in the bacterial cell wall.

Journal of Dental Research, Vol. 56, No. 8, 977-982 (1977)
DOI: 10.1177/00220345770560082601
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