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Journal of Dental Research
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Basic Biological Sciences

Remodeling of Compact Bone Studied with Lead Acetate as an Intravital Stain

Peter K-J. Yen

Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, Massachusetts 02115, USA

James H. Shaw

Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, Massachusetts 02115, USA

Remodeling of the osteons or Haversian canal system in compact bone was studied in young monkeys that received serial injections of lead acetate as an intravital strain. The successive stages of the formation of an osteon have been demonstrated. The rate of the filling of the lamellar bone decelerated as the lumen of the Haversian canal decreased. The total formation time of individual osteons was estimated.

Journal of Dental Research, Vol. 56, No. 8, 961-966 (1977)
DOI: 10.1177/00220345770560082201
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P. K-J. Yen, K. Moin, and J. H. Shaw
Remodeling of Cancellous Bone in Young Monkeys
Journal of Dental Research, February 1, 1978; 57(2): 388 - 394.
[Abstract] [PDF]