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Journal of Dental Research
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Effects of GK-101 (NMG) and Sodium Hypochlorite on Salivary Amylase Activity

Charles M. Habib

Tufts University School of Dental Medicine, Boston, Massachusetts 02111, USA

Joseph H. Kronman

Tufts University School of Dental Medicine, Boston, Massachusetts 02111, USA

Melvin Goldman

Tufts University School of Dental Medicine, Boston, Massachusetts 02111, USA

Stuart Cushner

Tufts University School of Dental Medicine, Boston, Massachusetts 02111, USA

A study was designed to assess the effects of the sodium salt of N-monochloroglycine (NMG) and sodium hypochlorite on the activity of salivary amylase. Concentrations of each agent were varied to determine the concentration at which the threshold and total inhibition of enzyme would be obtained. The data indicated that NMG at concentrations of 0.10% (w/v) does not affect amylase activity, whereas sodium hypochlorite at concentrations of 0.05% (w/v) totally inhibits salivary amylase activity.

Journal of Dental Research, Vol. 56, No. 6, 665-669 (1977)
DOI: 10.1177/00220345770560061601
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