This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ostrom, C. A. Articles by McGhee, J. R. Search for Related Content PubMed PubMed Citation Articles by Ostrom, C. A. Articles by McGhee, J. R. Social Bookmarking                         What's this?

Microbial Characterization of an Experimental Cariogenic Plaque in Man

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Theodore Koulourides

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Frances Hickman

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Jerry R. McGhee

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Experimentally induced plaque seemed to originate by direct contact inoculation from the vestibular mucosa and saliva. During the next seven days, this plaque developed its own characteristics. Populations of Streptococcus mutans, usually less than 2% of total streptococci population in plaques that were less than three days old, increased between days 3 and 7. Proportions of S sanguis, high in early samples, decreased after day 3. Populations of S salivarius, which usually outnumbered other streptococci, fluctuated widely through day 3, and then increased in proportion in subjects who were more productive of experimental caries, but decreased in subjects who were less productive. Proportions of plaque flora comprising lactobacilli paralleled those of S salivarius.

Journal of Dental Research, Vol. 56, No. 6, 550-558 (1977)
DOI: 10.1177/00220345770560060101


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				P.D. Marsh The Role of Microbiology in Models of Dental Caries Advances in Dental Research, November 1, 1995; 9(3): 244 - 254. [Abstract] [PDF]

				J.M. ten Cate and P.D. Marsh Procedures for Establishing Efficacy of Antimicrobial Agents for Chemotherapeutic Caries Prevention Journal of Dental Research, March 1, 1994; 73(3): 695 - 703. [Abstract] [PDF]

				L.M.D. Macpherson, T.W. MacFarlane, T.C. Aitchison, and K.W. Stephen The Effect of Sucrose Application and Implantation of Mutans Streptococci on the Microbial Composition of Three-week Experimental Plaque--An in situ Study Journal of Dental Research, November 1, 1990; 69(11): 1706 - 1711. [Abstract] [PDF]

				L.M.D. Macpherson, T.W. MacFarlane, and K.W. Stephen An Intra-oral Appliance Study of the Plaque Microflora Associated with Early Enamel Demineralization Journal of Dental Research, November 1, 1990; 69(11): 1712 - 1716. [Abstract] [PDF]

				P. Arneberg, B. Ogaard, A. Aa. Scheie, and G. Rolla Selection of Streptococcus mutans and Lactobacilli in an Intra-oral Human Caries Model Journal of Dental Research, October 1, 1984; 63(10): 1197 - 1200. [Abstract] [PDF]

				L. W. Borden, C. A. Ostrom, and T. Koulourides Establishment of Potentially Cariogenic Streptococci in an Experimental Human Plaque. I: Streptococcus mutans Journal of Dental Research, March 1, 1980; 59(3): 588 - 593. [PDF]