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Changes in Rat Parotid Salivary Proteins Induced by Chronic Isoproterenol Administration

Murray R. Robinovitch

Department of Oral Biology, School of Dentistry, and Center for Research in Oral Biology, University of Washington, Seattle, Washington 98195, USA

Patricia J. Keller

Department of Oral Biology, School of Dentistry, and Center for Research in Oral Biology, University of Washington, Seattle, Washington 98195, USA

Dorthea A. Johnson

Department of Oral Biology, School of Dentistry, and Center for Research in Oral Biology, University of Washington, Seattle, Washington 98195, USA

Jeanne M. Iversen

Department of Oral Biology, School of Dentistry, and Center for Research in Oral Biology, University of Washington, Seattle, Washington 98195, USA

Dorothy L. Kauffman

Department of Oral Biology, School of Dentistry, and Center for Research in Oral Biology, University of Washington, Seattle, Washington 98195, USA

Changes in the rat parotid gland and its secretion, brought about by chronic isoproterenol administration, were studied. In addition to the expected enlargement, morphological and biochemical analyses of the glands showed evidence of changes in the secretory components. Chromatographic and electrophoretic experiments revealed both qualitative and quantitative changes in the secretory proteins.

Journal of Dental Research, Vol. 56, No. 3, 290-303 (1977)
DOI: 10.1177/00220345770560031501


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