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Journal of Dental Research
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Immune Dysfunction and Dental Caries: A Preliminary Report

M.F. Cole

Institute of Dental Research and Department of Microbiology, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

R.R. Arnold

Institute of Dental Research and Department of Microbiology, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

M.J. Rhodes

Institute of Dental Research and Department of Microbiology, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Jerry R. McGhee

Institute of Dental Research and Department of Microbiology, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

This study was undertaken in order to correlate the immune status of persons with various types of immune dysfunctions with the incidence of dental caries. Preliminary data on caries experience and the microbial composition of plaque in these individuals are presented. The findings suggest that persons with immunoglobulin dysfunctions have a greater susceptibility to dental caries and have a greater frequency of harboring S mutans than do normal persons.

Journal of Dental Research, Vol. 56, No. 3, 198-204 (1977)
DOI: 10.1177/00220345770560030201
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